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suPAR is a protein in the blood. If an individual’s suPARnostic® level is very high, there is an increased chance of negative outcome (e.g. mortality) if appropriate treatment is not administered at the earliest. Appropriate treatment should result in a lowered suPARnostic® level. Thus, by measuring an individual’s suPARnostic® level, the prognosis is supported, the need for therapy is indicated and the effect of treatment can be monitored.