The value of suPAR for the General Practitioner
With the suPARnostic® prognosis for risk of disease progression there is now a reliable tool to aid in prioritizing patients. Identifying a patient’s suPARnostic® level upon presentation to hospitals or a General Practitioner’s office will enable physicians to assess which patients require immediate attention and further testing in order to ensaure timely treatment.
The suPAR level is associated with presence, severity and progression of disease, and in unselected patients, suPAR is one of the strongest prognostic biomarkers available to date.
suPARnostic® as a predictor of lifestyle related events
For lifestyle related events several published studies show that:
• Elevated suPARnostic® levels prognosticate an underlying health problem
• Lifestyle impacts the suPARnostic® level
• Without intervention individuals with high suPAR levels are at high risk of developing cardiovascular diseases, type-2 diabetes, cancer etc.
How suPARnostic® works
A patient is admitted to the ED for observation
The patient’s blood sample is drawn
The patient’s suPAR level is measured
The physician gets the result and makes a triage decision
suPAR level < 4 ng/ml
Supports patient discharge
suPAR level > 6 ng/ml
Supports patient hospitalisation
suPAR is a significant independent predictor of mortality of ED patients
|n = 4,343||Patients dead after 30 days||Patients alive after 30 days||PPV/NPV|
|suPAR ≥6 ng/ml||133||509||PPV|
|suPAR >3 and l||77||1,580|
|suPAR ≤3 ng/ml||14||2,030||NPV|
(suPAR ≤3 versus
Source: Rasmussen LJH, Ladelund S, Haupt TH, et al. Emerg Med J 2016;33:769-775
Documented by 700+ publications
suPAR is a prognostic tool that reflects the extent of activation of our immune system non-specific to any individual disease.
Here you can find a short summary of the research done on suPAR within 12 groups of disease areas and see how the suPAR level is affected within each type of disease.
“The key challenge for the ER is to identify ill patients faster, make diagnoses faster, find the right specialist faster and initiate the right treatment faster.”
MD, Chief Physician Inger Søndergaard, Herlev Hospital, Copenhagen