Availability of suPAR in emergency departments may improve risk stratification

Sun Jan 27 2019

New abstract published in Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine;

“Availability of suPAR in emergency departments may improve risk stratification: A secondary analysis of the TRIAGE III trial” by Schultz M et al.

Results:

“The study included 4420 patients with an available triage category and suPAR measurement.
suPAR was significantly better in predicting mortality than triage; AUC 0.85 vs. 0.71, P < 0.001.

Combining suPAR and triage yielded an AUC of 0.87.
The Youden’s cut-off of suPAR was 5.9 ng/mL and reclassified triage using this value resulted in a more accurate risk stratification regarding hospital admission and mortality.

Conclusion:

“Addition of the prognostic biomarker suPAR to triage potentially improves prediction of seven-day mortality in the emergency department.
Measurement of suPAR in relation to the triage process may allow a more accurate identification of ED patients at high and low risk of short-term mortality and enable a subsequent reclassification of patients.”

pdfLink to publication here

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