suPAR levels reliably predict mortality in patients with suspected AMI
Mon Apr 08 2019
New abstract published in Clinical Research in Cardiology;
“Predictive value of suPAR for mortality in patients with suspected myocardial infarction” by Sörensen NA et al.
Conclusion:
“Our study demonstrates that suPAR levels reliably predict mortality in the very heterogeneous group of patients presenting with symptoms suggestive of myocardial infarction in the emergency department. It, therefore, represents a valuable biomarker for risk estimation in this high-risk population”
and furthermore that
“In our study, suPAR alone achieved prognostic power comparable to the GRACE Score, a highly validated tool for predicting 6-month outcome in patients with ACS and a guideline recommended score for indicating patients as low risk after MI has been ruled out. Although suPAR did not improve GRACE score-based risk stratification substantially, the fact that a score, consisting of eight major risk factors including high-sensitivity troponin I, did not perform significantly better than the information derived by a single biomarker is remarkable.”