suPAR has excellent prognostic utility in predicting severe COVID-19 complications

Wed Apr 14 2021

Admission levels of Soluble Urokinase Plasminogen Activator Receptor (suPAR) Associate with Development of Severe Complications in Hospitalised COVID-19 Patients: A Prospective Cohort Study

Published in the International Journal of Infectious Diseases

A brand new study discloses that suPAR has excellent prognostic utility in predicting severe COVID-19 complications in hospitalized patients.

The ongoing pandemic exerts continuous pressure on hospitals. The current standard of care for triaging COVID-19 patients relies on routine clinical and laboratory assessment but offers limited prognostic information.

The study’s results demonstrate that COVID-19 patients with increased baseline suPAR levels are at a high risk of developing complications, which can significantly improve COVID-19 triage. It is essential to correctly identify patients that may be safely discharged home, those who need hospitalization, and those at risk of deterioration, potentially requiring ICU admission.

Highlights:

  • suPAR has been suggested as a good prognosis for severe complications of COVID-19.
  • COVID-19 patients with increased suPAR are at high risk of developing complications
  • Increasing suPAR by 1 ng/mL leads to 58% rise in the risk of getting complications.

suPAR has excellent prognostic utility in predicting severe COVID-19 complications

– Oulhaj et al, International Journal of Infectious Diseases, April 2021

Read the study here

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published suPAR studies in leading medical journals

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suPAR is used in clinical routine in 38 hospitals

38 hospitals use suPAR in clinical routine for triage of patients in the Emergency Departments and COVID-19 units. Clinical routine is defined by the placement of two Purchasing Orders within the last 12 months rolling. This period covers October 1, 2021, until September 30, 2022.
Some hospital locations cannot be disclosed due to confidentiality.

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