suPAR in Acute Triage

suPAR is a prognostic tool reflecting the extent of activation of our immune system non-specific to any individual disease.

This is the key advantage: The suPAR-level is, across diseases, directly linked to morbidity and mortality and therefore can be used to discriminate between non-survivors and survivors.

In Acute Triage, this will allow the hospital to:

  • Identify, treat and hospitalize those first who need it most:
    Ill patients with inflammation associated with an increased disease severity, readmission and mortality risk (elevated suPAR-level).
  • Identify those who can be discharged following treatment because their prognosis is good (low suPAR-level), which will
    • Shorten the average patient-length-of-stay
    • Free up beds in the Emergency Department
    • Lead to significant cost savings for the hospital
A drawing of what suPAR is and how it can be used

suPARnostic® Patient Guideline: suPARnostic® improves patient care and reduces healthcare costs by classifying 34% more patients into low-risk category. 1

suPAR in Clinical Use

suPAR is truly a novel biomarker and the concept of adding the prognostic information of patient risk status gained from measuring suPAR to clinical decision making is starting to be applied in medical practices.

The suPAR level is associated with presence, severity and progression of disease, and in unselected patients, suPAR is one of the strongest prognostic biomarkers available to date.

“suPARnostic® … provide[s] quick and reliable results in less than one hour from patient sampling to results in the hands of the clinicians.”

Claus Lohman Brasen, Senior hospital physician, PhD, Dept. of Biochemistry and Immunology, Lillebaelt Hospital, Denmark
ViroGates Company announcement no. 15 – 2019

suPARnostic® is developed to measure the amount of suPAR protein in human blood. If an individual’s suPARnostic® level is very high, there is an increased risk of a negative outcome (e.g. mortality). Appropriate treatment should result in a lowered suPARnostic® level.

suPARnostic® can improve the way seemingly low risk patients are managed – a low suPAR level helps avoid time and resources spent on further investigations, an elevated suPAR level is an indication that the patient is at higher risk of not surviving and it should be further investigated if this is caused by one or more developing diseases.

By measuring an individual’s suPARnostic® level, the patients risk of non-survival will be determined, allowing the doctor to prioritize selection of treatment and monitoring.

1: Schultz et al. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2019, 27:43