The following factors are associated with an elevated suPAR level:
Low HDL cholesterol/high LDL cholesterol1–3
Moreover, an elevated suPAR level is associated with future incidence of:
Type 2 diabetes1
Finally, a change towards a healthier lifestyle is associated with a suPAR decrease – and the resultant suPAR is predictive of outcome (mortality). Hence, suPAR is not a death sentence – it is an early warning signal8.