suPAR is a marker of chronic inflammation
Patients with high suPAR have a chronically activated immune system, that is not capable of fighting disease.
suPAR is elevated in elderly with comorbidities and capture the most fragile patients. In acute medical patients in general, suPAR is a strong marker of 30-day readmission and mortality1,2.
suPAR has been investigated in several viral infections, including HIV, HCV, Crimean-Congo hemorrhagic fever and hantavirus. In all cases, suPAR is associated with clinical severity and mortality3-6.