Study: Linking Stressful Life Events and Chronic Inflammation Using suPAR (Soluble Urokinase Plasminogen Activator Receptor) Stressful life events have been linked to declining health, and inflammation has been proposed as a physiological mechanism that might [...]
Find relevant information about suPAR news the most groundbreaking studies, case studies, and stories of suPAR success and application.
Review: Plasminogen System in Pathophysiology of Sepsis: Upcoming Biomarkers Severe hemostatic disturbances and impaired fibrinolysis occur in sepsis. In the most serious cases, the dysregulation of fibrinolysis contributes to septic shock, disseminated intravascular coagulation (DIC), [...]
Podocyte injury caused by sera from FSGS patients is mediated by CD40 and suPAR and can be blocked by human anti-uPAR and anti-CD40 antibodies.
Study: Perturbations in podocyte transcriptome and biological pathways induced by FSGS-associated circulating factors CD40 and suPAR mediate podocyte injury caused by sera from FSGS patients and can be blocked by human anti-uPAR and anti-CD40 antibodies. [...]
Combining clinical scoring systems with biomarkers might result in a more accurate mortality prediction than a clinical scoring system or biomarker alone
New study: Soluble urokinase plasminogen activator receptor and procalcitonin for risk stratification in patients with suspected infection in the emergency department: a prospective cohort study Early identification of patients at risk of clinical deterioration may [...]
suPAR assay in clinical routine: evaluation one year after introduction in high automation core lab of the A. Gemelli hospital
suPAR assay in clinical routine: evaluation one year after introduction in high automation core lab of the A. Gemelli hospital An article indicating how suPAR was implemented in the A. Gemelli Hospital (Rome, Italy), beyond [...]
The Journal of Clinical Investigation states: “Using clinical, genetic and experimental data, a collaborative study between researchers from USA, Sweden and Denmark shows that suPAR is a pathogenic factor for cardiovascular disease”. The study used a [...]
NEW STUDY Soluble urokinase plasminogen activator receptor and survival in elective cardiac surgery Results Besides long-term mortality, the biomarker score had an excellent performance in predicting one-year mortality and hospitalization due to heart failure. [...]
Association between variables measured in the ambulance and in-hospital mortality among adult patients with and without infection: a prospective cohort study
NEW STUDY Association between variables measured in the ambulance and in-hospital mortality among adult patients with and without infection: a prospective cohort study Conclusions: suPAR ≥ 8.0 ng/mL was associated with mortality in patients [...]