Triage suPARcharged

The suPAR biomarker predicts critical illness across diseases by measuring the level of activation in the immune response.

suPARnostic® is a reliable prognostic tool that enables healthcare professionals to make quick and informed patient triaging decisions at emergency departments.

How to interpret suPAR results

Empowering clinical decisions

suPARnostic® empowers healthcare professionals to lead patient triage with confidence by making better-informed decisions backed by reliable biological data across diseases.

Implementing the biomarker suPAR in triage and clinical care delivers faster and safer patient discharges, reduces re-admissions, unnecessary admissions, as well as hospital length-of-stay. – Freeing up critical resources, valuable time, and saving hospital beds for those who need them. Incorporating suPAR in triage has benefits for patients, clinicians and Emergency Department.

suPARnostic® video

Improve patient care

Up to 22% reduction in hospital admissions and up to 6% reduction in hospital length-of-stay per patient


Reduce healthcare costs

Up to €100-380 savings per admission depending on medical specialty and geography


Empower clinical staff

Get more information to make more confident decisions to potentially reduce uncertainty


“it is essential to have the help of biomarkers, such as suPAR, which can support the discharge decision”

Juan González del Castillo,
Dr PhD, Hospital Clínico San Carlos, Spain
suPAR News Vol. 1, April 2019

How suPARnostic® works at the emergency department

Step 1

A patient is admitted to the emergency department for observation

Step 2

The patient’s blood sample is drawn

Step 3

The patient’s suPAR level is measured at the central lab
(~20 minutes) and fits existing hospital workflow.

Step 4

The physician gets the result and makes a triage decision

suPAR is a significant independent predictor of mortality of emergency department patients

AllsuPAR ≤ 4 ng/mLsuPAR > 4 and < 6 ng/mLsuPAR ≥ 6 ng/mlP Value
Discharge < 24 H N785462215108< 0.001
30 Day pre-admitted N379131121127< 0.001
Readmission 30 Days N3681531141010,14
Mortality 7 Days N343922< 0.001
Mortality 30 Days N8162550< 0.001
Mortality 90 Days N13884387< 0.001

* Santeri, S., Peter, A.A., Kristiina, N. et al. suPAR cut-offs for stratification of low, medium, and high-risk acute medical patients in the emergency department. BMC Emerg Med 21, 149 (2021).

suPAR compared to other biomarkers

* suPAR values should be used in conjunction with clinical findings and the results of other laboratory parameters. suPAR values alone are not indicative of the need for mechanical ventilation.

1. Soluble urokinase plasminogen activator receptor (suPAR) as an early predictor of severe respiratory failure in patients with COVID-19 pneumonia. Rovina N et al. Crit Care. 2020 4(1):187. (LINK:
2. Soluble Urokinase Receptor (SuPAR) in COVID-19-Related AKI. Azam TU et al. J Am Soc Nephrol. 2020 (LINK:
3. Soluble Urokinase-Guided Anakinra To Prevent Respiratory Failure In COVID-19: A Single-Arm Trial. Kyriazopoulou E et al. (preprint, link to be provided when available)
4. Soluble Urokinase Plasminogen Activator Receptor: A Biomarker for Predicting Complications and Critical Care Admission of COVID-19 Patients. Chalkias A et al. Mol Diagn Ther. 2020 (5):517-521. (LINK:
5. COVID-19 and pneumonia: a role for the uPA/uPAR system. D’Alonzo D et al. Drug Discov Today. 2020 (8):1528-1534. Review. (LINK:


published suPAR studies in leading medical journals

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JAMA Pediatrics Logo

The suPARnostic® brand consists of 4 products:

Quick Triage

A Point of Care Solution


For Automated Systems


Clinical and Research

suPARnostic POC+


Point-of-care finger prick

suPAR is used in clinical routine in 48 hospitals

48 hospitals use suPAR in clinical routine for triage of patients in the Emergency Departments and COVID-19 units. Clinical routine is defined by the placement of two Purchasing Orders within the last 12 months rolling.
This period covers January 1, 2022, until December 31, 2022. Some hospital locations cannot be disclosed due to confidentiality.

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